Select Publications:
(undergraduate students highlighted in Blue)
1. Ternary structure of Plasmodium vivax N-myristoyl transferase (PvNMT) with myristoyl-CoA and inhibitor IMP-0001173. Acta Crystallographica F. 2024. C. Bolling, A. Mendez, S. Taylor, S. Makumire, A Reers, R. Zigweid, S. Subramanian, D. M. Dranow, B. Staker, T. E. Edwards, E W. Tate, A. S. Bellg, P. J. Myler, O. A. Asojo, and G. Chakafana*
2. Structure of Plasmodium vivax N-myristoyl transferase with inhibitor IMP-1088 - exploring an NMT inhibitor for antimalarial therapy. ACTA Cryst. 2024. A. Mendez, C. Bolling, S. Taylor, S. Makumire, A. Reers, R. Zigweid, S. Subramanian, D.M. Dranow, B. Staker, T.E. Edwards, E.W.Tate, A.S. Bell, P.J. Myler, O.A. Asojo and G. Chakafana*
3. Structures of Brucella ovis leucine-, isoleucine-, valine-, threonine- and alanine-binding protein reveal a conformationally flexible peptide-binding cavity. Acta Crystallographica F. 2024. G. Chakafana*, R. Boswell, A. Chandler, K A. Jackson, S. Neblett, T. Postal, S. Subramanian, J. Abendroth, P J. Myler and O A. Asojo*
4. Swapping the linkers of canonical Hsp70 and Hsp110 chaperones compromises both self-association and client selection. SSRN 4670632. 2024 Chakafana, G., Middlemiss, C.J., Zininga, T. and Shonhai, A
5. Insertion of GGMP repeat residues of Plasmodium falciparum Hsp70-1 in the lid of DnaK adversely impacts client recognition. International Journal of Biological Macromolecules, 255. 2024. Dongola, T.H., Chakafana, G., Middlemiss, C., Mafethe, O., Mokoena, F., Zininga, T. and Shonhai, A
6. Proteomic profiling in patients with peripartum cardiomyopathy: a biomarker study of the ESC EORP PPCM registry. Heart Failure, 11(12). 2023. Kodogo, V., Viljoen, C., Hoevelmann, J., Chakafana, G., Tromp, J., Farhan, H.A., Goland, S., van der Meer, P., Karaye, K., Kryczka, K. and Hilfiker-Kleiner, D
7. Characterization of a novel linker segment of the Plasmodium falciparum cytosol localised Hsp110 chaperone. 2021. International Journal of Biological Macromolecules. G. Chakafana, P. T. Mudau, T. Zininga, A. Shonhai
8. E. coli-based complementation assay and biochemical analyses reveal an essential role of the GGMP motif of Plasmodium falciparum Hsp70-1 chaperone. 2021. International Journal of Molecular Sciences. S. Makumire, T. Dongola, G. Chakafana, L. Tshikonwane, C.T. Chauke, T. Maharaj, T. Zininga, A. Shonhai